BDBM50096300 CHEMBL3585452

SMILES Cc1cncc(c1)-c1cnc(NC2CCNCC2)c2[nH]c(=O)c(C)cc12

InChI Key InChIKey=PAGDGWOISBNVEC-UHFFFAOYSA-N

Data  13 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50096300   

TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50096300(CHEMBL3585452)
Affinity DataIC50:  1.26E+3nMAssay Description:Displacement of histone H4 peptide from FLAG-6His-Tev-ATAD2 (981 to 1121) (unknown origin) expressed in Escherichia coli BL21 (DE3) after 30 mins by ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50096300(CHEMBL3585452)
Affinity DataIC50:  3.98E+3nMAssay Description:Inhibition of ATAD2 in human PBMC assessed as inhibition of LPS-stimulated IL-6 release after 18 to 24 hrsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50096300(CHEMBL3585452)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of ATAD2 (unknown origin) by TR-FRET assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetATPase family AAA domain-containing protein 2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50096300(CHEMBL3585452)
Affinity DataKd:  2.50E+3nMAssay Description:Binding affinity to FLAG-6His-Tev-ATAD2 (950 to 1148) (unknown origin) expressed in Escherichia coli BL21 (DE3) by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed